Publications



Signaling through NO and cGMP-dependent protein kinases.


Schlossmann J, Feil R & Hofmann F

Ann. Med. 2003, 35, 21 – 27 

Impaired insulin secretion and glucose tolerance in β cell-selective Cav1.2 Ca2+-channel null mice.


Schulla V, Renström E, Feil R, Feil S, Franklin I, Gjinovci A, Jing XJ, Laux D, Lundquist I, Magnuson MA, Obermüller S, Olofsson CS, Salehi A, Wendt A, Klugbauer N, Wollheim CB, Rorsman P & Hofmann F

EMBO J. 2003, 22, 3844 – 3854

Individual cerebellar Purkinje cells express different cGMP phosphodiesterases (PDEs): In Vivo phosphorylation of cGMP-specific PDE (PDE5) as an indicator of cGMP-dependent protein kinase (PKG) activation.


Shimizu-Albergine M, Rybalkin SD, Rybalkina IG, Feil R, Wolfsgruber W, Hofmann F & Beavo JA

J. Neurosci. 2003, 23, 6452 – 6459

The hyperpolariation-activated channel HCN4 is required for the generation of pacemaker action potentials in the embryonic heart.


Stieber J, Herrmann S, Feil S, Löster J, Feil R, Biel M, Hofmann F & Ludwig A

PNAS 2003, 100, 15235 – 15240

Alterations in the myocardial creatine kinase system precede the development of contractile dysfunction in beta(1)-adrenergic receptor transgenic mice.


Spindler M, Engelhardt S, Niebler R, Wagner H, Hein L, Lohse MJ & Neubauer S

Molecular basis for the different activation kinetics of the pacemaker channels HCN2 and HCN4.


Stieber J, Thomer A, Much B, Schneider A, Biel M & Hofmann F

J. Biol. Chem. 2003, 278, 33672 – 33680

Pore structure influences gating properties of the T-type Ca2+ channel a1G.


Talavera K, Janssens A, Klugbauer N, Droogmans G & Nilius B

J. Gen. Physiol. 2003, 121, 529 – 540

Extracellular Ca2+ modulates the effects of protons on gating and conduction properties of the T-type Ca2+ channel a1G (Cav3.1).


Talavera K, Janssens A, Klugbauer N, Droogmans G & Nilius B

J. Gen. Physiol. 2003, 121, 511 – 528

Autophosphorylation of cGMP-dependent Protein Kinase Type II.


Vaandrager AB, Hogema BM, Edixhoven M, van den Burg CMM, Bot AGM, Klatt P, Ruth P, Hofmann F, van Damme J, Vandekerckhove J & de Jonge HR

J. Biol. Chem. 2003, 278, 28651 – 28658

Investigation of the pharmaceutical and pharmacological equivalence of different Hawthorn extracts.


Vierling W, Brand N, Gaedcke F, Sensch KH, Schneider E & Scholz M

Phytomedicine 2003, 10, 8 – 16